Early to Midlife Smoking Trajectories and Cognitive Function in Middle-Aged US Adults: the CARDIA Study.

ABSTRACT:

Background

Smoking starts in early adulthood and persists throughout the life course, but the association between these trajectories and midlife cognition remains unclear.

Objective

Determine the association between early to midlife smoking trajectories and midlife cognition.

Design

Prospective cohort study.

Participants

Participants were 3364 adults (mean age = 50.1 ± 3.6, 56% female, 46% Black) from the Coronary Artery Risk Development in Young Adults (CARDIA) study: 1638 ever smokers and 1726 never smokers.

Main measures

Smoking trajectories were identified in latent class analysis among 1638 ever smokers using smoking measures every 2-5 years from baseline (age 18-30 in 1985-1986) through year 25 (2010-2011). Poor cognition was based on cognitive dom

SUBMITTER: Bahorik AL 

PROVIDER: S-EPMC8971217 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature