Prognostic significance of AP-2α/γ targets as cancer therapeutics.

ABSTRACT: Identifying genes with prognostic importance could improve cancer treatment. An increasing number of reports suggest the existence of successful strategies based on seemingly "untargetable" transcription factors. In addition to embryogenesis, AP-2 transcription factors are known to play crucial roles in cancer development. Members of this family can be used as prognostic factors in oncological patients, and AP-2α/γ transcription factors were previously investigated in our pan-cancer comparative study using their target genes. The present study investigates tumors that were previously found similar with an emphasis on the possible role of AP-2 factors in specific cancer types. The RData workspace was loaded back to R environment and 3D trajectories were built via Monocle3. The genes that me

SUBMITTER: Kolat D 

PROVIDER: S-EPMC8971500 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature