Iron (Fe)-doped mesoporous 45S5 bioactive glasses: Implications for cancer therapy.

ABSTRACT: The utilization of bioactive glasses (BGs) in cancer therapy has recently become quite promising; herein, a series of Fe-doped mesoporous 45S5-based BGs (MBGs) were synthesized via the sol-gel method in the presence of Pluronic P123 as a soft template. The physico-chemical and biological properties of the prepared glasses were well-characterized through structural assessments, thermal analyses, and electron microscopic studies. Electrochemical analyses, including cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), were also performed to investigate the actual potential of the Fe₂O₃-containing MBGs in modulating the Fenton's reaction. The XRD results confirmed the glassy state of the Fe-doped samples before immersion in simulated body fluid (SBF).

SUBMITTER: Kermani F 

PROVIDER: S-EPMC8972012 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature