Role of left atrial appendage occlusion in patients with HeartMate 3.

ABSTRACT:

Objectives

Left atrial appendage occlusion (LAAO) at the time of implantation may reduce thromboembolic events (TEs) during continuous-flow left ventricular assist device support. The HeartMate 3 (HM3) reduces TEs overall, but the efficacy of LAAO in HM3 is unknown.

Methods

Adults receiving first HM3 implantation from November 2014 through December 2019 at a single, large medical centre were retrospectively reviewed. TEs included device thrombosis and ischaemic stroke. Patients were classified by whether they received LAAO or not. Incidence of TEs was compared between groups using cumulative incidence curves with competing risks (death and heart transplant) and risk factors for TEs were assessed with Fine and Gray competing risk regression.

Results

A total of 182 pati

SUBMITTER: Melehy A 

PROVIDER: S-EPMC8972327 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature