Rare case of Histoplasma capsulatum endocarditis in a patient with a prosthetic valve.

ABSTRACT:

Background

Diagnosis of fungal endocarditis can be challenging, especially among cases with negative blood culture results. Of fungal endocarditis cases, Histoplasma capsulatum constitutes an even smaller proportion with ∼58 prior cases reported. Due to the rarity of histoplasmosis endocarditis and thus limited data, there is no current diagnostic guideline for testing within culture negative infective endocarditis.

Case summary

Our patient was a 58-year-old female presenting with worsening dyspnoea, hypotension, and near-syncope. In this case report, we depict the clinical presentation and diagnosis of H. capsulatum endocarditis in a female patient with a prosthetic aortic valve and negative blood cultures. We further demonstrate the rising risk of fungal endo

SUBMITTER: Manning EM 

PROVIDER: S-EPMC8972819 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature