SARS-CoV-2 Variants of Concern Increased Transmission and Decrease Vaccine Efficacy in the COVID-19 Pandemic in Palembang Indonesia.

ABSTRACT:

Background and aim

The number of COVID-19 cases surging despite the large scale of health promotion campaigns. This study aimed to find disease transmissibility and affected vaccine efficacy associated with the mutation of the SARS-CoV-2 variant of concern.

Methods

The study was a descriptive temporal survey design with secondary ecological data: the whole-genome sequence (WGS) from the Global Initiative on Sharing Avian Influenza (GISAID) and COVID-19 data from the Palembang City Health Office website. Bioinformatics software was used to detect mutations.

Results

Palembang submitted 43 whole genome sequences, 13 of which were Pangoline sequences classifications.

Conclusions

The two concern variations, Alpha and Delta, were associated with increased transmissio

SUBMITTER: Ghiffari A 

PROVIDER: S-EPMC8972875 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature