Associations between bone mineral density and coronary artery calcification: a systematic review and meta-analysis.

ABSTRACT:

Background

The studies about the correlation between bone mineral density (BMD) and coronary arterial calcification (CAC) were still controversial. The aim of this study was to conduct a meta-analysis to evaluate the association between BMD and CAC.

Methods

We systematically searched PubMed, Embase, Google scholar and Cochrane library for observational studies. We pooled odds ratio (OR) or correlation coefficient, and 95% confidence interval (CI) of the studies. Continuous data were pooled by mean difference (MD). Sub-group analysis was applied to investigate sources of heterogeneity. Funnel plots for publication bias was also performed.

Results

Seventeen studies met the inclusion criteria. Pooled ORs for the prevalence of CAC in patients with low BMD versus patients

SUBMITTER: Zhang P 

PROVIDER: S-EPMC8972925 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature