Base-Free Synthesis and Photophysical Properties of New Schiff Bases Containing Indole Moiety.

ABSTRACT: Schiff bases represent an essential class in organic chemistry with antitumor, antiviral, antifungal, and antibacterial activities. The synthesis of Schiff bases requires the presence of an organic base as a catalyst such as piperidine. Base-free synthesis of organic compounds using a heterogeneous catalyst has recently attracted more interest due to the facile procedure, high yield, and reusability of the used catalyst. Herein, we present a comparative study to synthesize new Schiff bases containing indole moieties using piperidine as an organic base catalyst and Au@TiO₂ as a heterogeneous catalyst. In both methods, the products were isolated in high yields and fully characterized using different spectral analysis techniques. The catalyst was reusable four times, and the activi

SUBMITTER: Soliman AIA 

PROVIDER: S-EPMC8973100 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature