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Consumption and cost trends of EGFR TKIs: influences of reimbursement and national price negotiation.


ABSTRACT:

Background

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been widely used in the treatment of EGFR mutation non-small-cell lung cancer. The Chinese government has made great efforts to improve the availability and affordability of these drugs. The aim of this study was to investigate the trends in the consumption and cost of EGFR TKIs in Nanjing, a developed city in China, and evaluate the influence of health insurance coverage and national price negotiation on drug consumption.

Methods

Data about EGFR TKIs applications in 2010-2019 were extracted from Jiangsu Medicine Information Institute. Five types of EGFR TKIs were included. Consumption was expressed in defined daily doses (DDDs) and expenditure. The correlation between defined daily cos

SUBMITTER: Wu D 

PROVIDER: S-EPMC8973903 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature