Still SDAPing Along: 20 Years of the Structural Database of Allergenic Proteins.

ABSTRACT: The introduction of plant extracts to mitigate the symptoms of "hay fever", about a century ago, led to discoveries beginning sixty years ago on determining the sequences and eventually structures of allergenic proteins. As more proteins were cloned, there was a need to rapidly identify and categorize those with significant similarity to known allergens. The Structural Database of Allergenic Proteins (SDAP) was created at the beginning of the 21st century as the first cross-referenced website to allow rapid overview of the structures and sequences of allergenic proteins. SDAP provides a way to identify sequence and functional similarities between these proteins, despite the complex nomenclature system based on the Latin names of their different sources. A rapid FASTA search simplifies grou

SUBMITTER: Schein CH 

PROVIDER: S-EPMC8974667 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature