Allergological Importance of Invertebrate Glutathione Transferases in Tropical Environments.
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ABSTRACT:
SUBMITTER: Zakzuk J
PROVIDER: S-EPMC8974725 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
Allergological Importance of Invertebrate Glutathione Transferases in Tropical Environments.
Zakzuk Josefina J Lozano Ana A Caraballo Luis L
Frontiers in allergy 20210614
Glutathione-S transferases (GSTs) are part of a ubiquitous family of dimeric proteins that participate in detoxification reactions. It has been demonstrated that various GSTs induce allergic reactions in humans: those originating from house dust mites (HDM), cockroaches, and helminths being the best characterized. Evaluation of their allergenic activity suggests that they have a clinical impact. GST allergens belong to different classes: mu (Blo t 8, Der p 8, Der f 8, and Tyr p 8), sigma (Bla g ...[more]
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