Dataset Information
Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis.
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ABSTRACT:
SUBMITTER: Mitra S
PROVIDER: S-EPMC8974932 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Publications
Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis.
The Cochrane database of systematic reviews 20220401
<h4>Background</h4>Patent ductus arteriosus (PDA) is associated with significant morbidity and mortality in preterm infants. Cyclooxygenase inhibitors (COX-I) may prevent PDA-related complications. Controversy exists on which COX-I drug is the most effective and has the best safety profile in preterm infants.<h4>Objectives</h4>To compare the effectiveness and safety of prophylactic COX-I drugs and 'no COXI prophylaxis' in preterm infants using a Bayesian network meta-analysis (NMA).<h4>Search me ...[more]