Vaccination and COVID-19 Dynamics in Dialysis Patients.

ABSTRACT:

Background and objectives

Dialysis patients have a high mortality risk after coronavirus disease 2019 (COVID-19) and an altered immunologic response to vaccines, but vaccine clinical effectiveness remains unknown in this population.

Design, setting, participants, & measurements

Using Bayesian multivariable spatiotemporal models, we estimated the association between vaccine exposure and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe infections (with hospital admission) in dialysis patients from simultaneous incidence in the general population. For dialysis patients, cases were reported within the French end-stage kidney disease REIN registry from March 11, 2020, to April 29, 2021, and vaccine exposure (first dose) was reported in weekly national surveys s

SUBMITTER: El Karoui K 

PROVIDER: S-EPMC8975027 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature