Dataset Information

Association between being underweight and excess body weight before SARS coronavirus type 2 infection and clinical outcomes of coronavirus disease 2019: Multicenter study.

ABSTRACT:

Objectives

The present study aimed to identify associations between extremes in body weight status (underweight and excess body weight) before a COVID-19 diagnosis and clinical outcomes in patients infected with SARS coronavirus type 2.

Methods

A multicenter cohort study was conducted in eight different states in northeastern Brazil. Demographic, clinical (previous diagnosis of comorbidities), and anthropometric (self-reported weight and height) data about individuals who tested positive for COVID-19 were collected. Outcomes included hospitalization, mechanical ventilation, and death. Multivariable logistic regression models, adjusted based on age, sex and previous comorbidities, were used to assess the effects of extremes in body weight status on clinical outcomes.

Results

A total of 1308 individuals were assessed (33.6% were elderly individuals). The univariable analyses showed that only hospitalization was more often observed among underweight (3.2% versus 1.2%) and overweight (68.1% versus 63.3%) individuals. In turn, cardiovascular diseases were more often observed in all clinical outcomes (hospitalization: 19.7% versus 4.8%; mechanical ventilation: 19.9% versus 13.5%; death: 21.8% versus 14.1%). Based on the multivariable analysis, body weight status was not associated with risk of hospitalization (underweight: odds ratio [OR]: 1.10; 95% confidence interval [CI] 95%, 0.50-2.41 and excess body weight: OR: 0.81; 95 CI, 0.57-1.14), mechanical ventilation (underweight: OR: 0.92; 95% CI, 0.52-1.62 and excess weight: OR: 0.90; 95% CI, 0.67-1.19), and death (underweight: OR: 0.61; 95% CI, 0.31-1.20 and excess body weight: OR 0.88; 95% CI, 0.63-1.23).

Conclusions

Being underweight and excess body weight were not independently associated with clinical outcomes in patients with COVID-19 in the herein analyzed cohort. This finding indicates that the association between these variables may be confounded by both age and comorbidities.

SUBMITTER: Barros-Neto JA

PROVIDER: S-EPMC8975608 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Publications

Association between being underweight and excess body weight before SARS coronavirus type 2 infection and clinical outcomes of coronavirus disease 2019: Multicenter study.

Barros-Neto João Araújo JA Mello Carolina Santos CS Vasconcelos Sandra Mary Lima SML Bádue Gabriel Soares GS Ferreira Raphaela Costa RC Andrade Maria Izabel Siqueira de MIS Nascimento Carlos Queiroz do CQD Macena Mateus de Lima ML Silva José Adailton da JAD Clemente Heleni Aires HA Petribu Marina de Moraes Vasconcelos MMV Dourado Keila Fernandes KF Pinho Claudia Porto Sabino CPS Vieira Renata Adrielle Lima RAL Mello Leilah Barbosa de LB Neves Mariana Brandão das MBD Jesus Camila Anjos de CA Santos Tatiana Maria Palmeira Dos TMPD Soares Bruna Lúcia de Mendonça BLM Medeiros Larissa de Brito LB França Amanda Pereira de AP Sales Ana Lina de Carvalho Cunha ALCC Furtado Elane Viana Hortegal EVH Oliveira Alane Cabral AC Farias Fernanda Orrico FO Freitas Mariana Carvalho MC Bueno Nassib Bezerra NB

Nutrition (Burbank, Los Angeles County, Calif.) 20220401

<h4>Objectives</h4>The present study aimed to identify associations between extremes in body weight status (underweight and excess body weight) before a COVID-19 diagnosis and clinical outcomes in patients infected with SARS coronavirus type 2.<h4>Methods</h4>A multicenter cohort study was conducted in eight different states in northeastern Brazil. Demographic, clinical (previous diagnosis of comorbidities), and anthropometric (self-reported weight and height) data about individuals who tested p ...[more]

PMID: 35660497

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Dataset Information

Association between being underweight and excess body weight before SARS coronavirus type 2 infection and clinical outcomes of coronavirus disease 2019: Multicenter study.

Objectives

Methods

Results

Conclusions

Publications

Association between being underweight and excess body weight before SARS coronavirus type 2 infection and clinical outcomes of coronavirus disease 2019: Multicenter study.

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