Can Gastric Cancer Patients with High Mandard Score Benefit from Neoadjuvant Chemotherapy?

ABSTRACT: A high Mandard score may indicate the tumor is insensitive to chemotherapy. We analyzed tumor regression and lymph node response under different Mandard scores to assess the impact of Mandard score on prognosis. Methods. Mandard scores and ypN stage of postoperative pathological reports were recorded. The results were reviewed by a professional pathologist. The radiologist compared the tumor regression before and after chemotherapy by computed tomography (CT). The survival of all patients was obtained by telephone follow-up. Multivariate Cox regression was used to assess the relationship between overall risk of death and Mandard score, imaging evaluation, and ypN stage. Results. In the Mandard score (4-5) group, the median survival time for PR and ypN0 patients was 68.5 and 7

SUBMITTER: Kang WZ 

PROVIDER: S-EPMC8975703 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature