Granular honeycomb scaffolds composed of carbonate apatite for simultaneous intra- and inter-granular osteogenesis and angiogenesis.
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ABSTRACT:
SUBMITTER: Hayashi K
PROVIDER: S-EPMC8976130 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
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Granular honeycomb scaffolds composed of carbonate apatite for simultaneous intra- and inter-granular osteogenesis and angiogenesis.
Hayashi Koichiro K Yanagisawa Toshiki T Shimabukuro Masaya M Kishida Ryo R Ishikawa Kunio K
Materials today. Bio 20220326
Granular porous calcium phosphate scaffolds are used for bone regeneration in dentistry. However, in conventional granules, the macropore interconnectivity is poor and has varying size. Herein, we developed a productive method for fabricating carbonate apatite honeycomb granules with uniformly sized macropores based on extrusion molding. Each honeycomb granule possesses three hexagonal macropores of ∼290 μm along its diagonal. Owing to these macropores, honeycomb granules simultaneously formed ...[more]
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