The relationship between vascular endothelial growth factor expression and the risk of childhood nephroblastoma: systematic review and meta-analysis.

ABSTRACT:

Background

This study explores the correlation between vascular endothelial growth factor expression and the risk of childhood nephroblastoma.

Methods

PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang database were searched to collect independent study data published in China between 2010 and 2021 on the expression and significance of VEGF in childhood nephroblastoma, and literature heterogeneity was tested. The odds ratio (OR) value was used as the effect indicator. Meta-analysis software RevMan 4.2.2 was used, and the original data of each study were statistically processed to calculate the combined OR value and 95% confidence interval (CI).

Results

Twelve studies involving 1,226 cases of pediatric nephroblastoma were included

SUBMITTER: Liao W 

PROVIDER: S-EPMC8976676 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature