Long-term neurological outcomes of children with neuroblastoma with opsoclonus-myoclonus syndrome.

ABSTRACT:

Background

Neuroblastoma with opsoclonus-myoclonus syndrome (OMS-NB) is a rare disease in children. Few studies of long-term outcome of children with OMS-NB were conducted. This study aimed to review the rate of recovery of neurological symptoms and the long-term neurological outcomes of children with OMS-NB.

Methods

This study retrospectively assessed 14 children with OMS-NB diagnosed at Peking University First Hospital from May 2011 to November 2019. Demographic data, neurological symptoms, oncological status and treatments were retrospectively reviewed from the records. Neurological sequelae were recorded by clinical and remote follow-up.

Results

During the acute stage, myoclonus and ataxia were observed in all children while opsoclonus was observed in 10/14 childr

SUBMITTER: Sun Q 

PROVIDER: S-EPMC8976687 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature