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Ductal carcinoma in situ arising from fibroadenoma; a rare case with review of literature.
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ABSTRACT: Introduction
ibroadenoma (FA) is a common benign breast mass representing a group of hyperplastic breast lobules due to the deviation of normal development. This study aims to present a rare case of ductal carcinoma in situ (DCIS) associated with fibroadenoma.Case report
A 49-year-old married female presents with a right breast mass for five years. Core needle biopsy diagnosed the specimen as cellular complex fibroadenoma. A breast-lumpectomy and the histopathological examination of the surgical specimen confirmed ductal carcinoma in-situ.Discussion
Malignant changes within fibroadenomas typically happen at an older age, with the age of detection in the fifth decade. Complex fibroadenomas are more related to malignant transformation. Old age and strong family history are risk factors for malignant transformation of fibroadenomas.Conclusion
Fibroadenomas are common benign tumors. They can rarely be associated with DCIS. Therefore, the risk of malignancy should always be kept in mind.
SUBMITTER: Hammood ZD
PROVIDER: S-EPMC8977904 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Publications
Ductal carcinoma in situ arising from fibroadenoma; a rare case with review of literature.
Annals of medicine and surgery (2012) 20220302
<h4>Introduction</h4>ibroadenoma (FA) is a common benign breast mass representing a group of hyperplastic breast lobules due to the deviation of normal development. This study aims to present a rare case of ductal carcinoma in situ (DCIS) associated with fibroadenoma.<h4>Case report</h4>A 49-year-old married female presents with a right breast mass for five years. Core needle biopsy diagnosed the specimen as cellular complex fibroadenoma. A breast-lumpectomy and the histopathological examination ...[more]
