The effect of NPWT in wound healing and bacterial count on deep dermal burn injury model: An experimental study.

ABSTRACT:

Background

Sepsis is one of the main causes in burn victim's mortality. The use of negative pressure wound therapy (NPWT) provides an ideal environment to accelerate wound healing. We compare the use of normal saline (NS), intermittent NPWT, continuous NPWT and silver sulfadiazine in wound healing process.

Method

This study involved 6 Yorkshire pigs; each pig was induced with 20 burns on the flank area. Burns were divided into 4 treatment groups: NS gauze, intermittent NPWT, continuous NPWT, and silver sulfadiazine dressing. Burns were evaluated on day 1,3,7,14, and 21 for its morphology and bacterial colonization and on day 14 and 21 for the remaining burn surface area.

Result

Wound that received NPWT therapy appeared better in both granulation and crust formation. R

SUBMITTER: Resadita R 

PROVIDER: S-EPMC8977920 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature