Muscle strength and prediabetes progression and regression in middle-aged and older adults: a prospective cohort study.

ABSTRACT:

Background

Prediabetes progression is associated with increased mortality while its regression decreases it. It is unclear whether muscle strength is related to prediabetes progression or regression. This study investigated the associations of muscle strength, assessed by grip strength and chair-rising time, with prediabetes progression and regression based on the China Health and Retirement Longitudinal Study (CHARLS) enrolling middle-aged and older adults.

Methods

We included 2623 participants with prediabetes from CHARLS, who were followed up 4 years later with blood samples collected for measuring fasting plasma glucose and haemoglobin A1c. Grip strength (normalized by body weight) and chair-rising time were assessed at baseline and categorized into tertiles (low, middle

SUBMITTER: Qiu S 

PROVIDER: S-EPMC8978008 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature