Potential effect of amniotic fluid-derived stem cells on hyperoxia-induced pulmonary alveolar injury.

ABSTRACT:

Background

With the widespread of Coronavirus Disease 2019 pandemic, in spite of the newly emerging vaccines, mutated strains remain a great obstacle to supportive and preventive measures. Coronavirus 19 survivors continue to face great danger of contacting the disease again. As long as no specific treatment has yet to be approved, a great percentage of patients experience real complications, including among others, lung fibrosis. High oxygen inhalation especially for prolonged periods is per se destructive to the lungs. Nevertheless, oxygen remains the first line support for such patients. In the present study we aimed at investigating the role of amniotic fluid-mesenchymal stem cells in preventing versus treating the hyperoxia-induced lung fibrosis in rats.

Methods

The stu

SUBMITTER: Solaiman A 

PROVIDER: S-EPMC8978174 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature