Proton therapy for prostate cancer: current state and future perspectives.

ABSTRACT:

Objective

Localized prostate cancer can be treated with several radiotherapeutic approaches. Proton therapy (PT) can precisely target tumors, thus sparing normal tissues and reducing side-effects without sacrificing cancer control. However, PT is a costly treatment compared with conventional photon radiotherapy, which may undermine its overall efficacy. In this review, we summarize current data on the dosimetric rationale, clinical benefits, and cost of PT for prostate cancer.

Methods

An extensive literature review of PT for prostate cancer was performed with emphasis on studies investigating dosimetric advantage, clinical outcomes, cost-effective strategies, and novel technology trends.

Results

PT is safe, and its efficacy is comparable to that of standard photon-bas

SUBMITTER: Wu YY 

PROVIDER: S-EPMC8978248 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature