Cardiovascular-specific mortality among multiple myeloma patients: a population-based study.

ABSTRACT:

Introduction

Multiple myeloma (MM) survival has greatly improved in recent decades. MM is usually diagnosed at a median age of 66-70 years. MM patients do not necessarily die from primary cancer, so cardiovascular health may be a key factor threatening long-term survival. This study was designed to explore the cardiovascular disease mortality (CVM) trends in MM patients and compare them with those in the general population.

Methods

In total, 88,328 MM patients from the Surveillance, Epidemiology, and End Results (SEER) database (1975-2016) were included. Standardized mortality ratios (SMRs) were used to assess CVM risk.

Results

The CVM risk was significantly higher in MM patients than in the general population (SMR, 1.84 (95% CI, 1.78-1.89)). MM patients had the highe

SUBMITTER: Yin X 

PROVIDER: S-EPMC8978329 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature