Low cholesterol is not associated with depression: data from the 2005-2018 National Health and Nutrition Examination Survey.

ABSTRACT:

Background

Although high serum cholesterol is widely recognized as a major risk factor for heart disease, the health effects of low cholesterol are less clear. Several studies have found a correlation between low cholesterol and depression, but the results are inconsistent.

Methods

Data from the National Health and Nutrition Examination Survey (NHANES) 2005-2018 were utilized in this cross-sectional study. The analysis of the relationship between cholesterol and depression was performed at three levels: low total cholesterol, low high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol. The inclusion criteria were as follows: (1) people with low (<4.14 mmol/L) or normal (4.14-5.16 mmol/L) total cholesterol for Sample 1; people with low (<1 mmo

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC8978383 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature