Prospective association of dietary soy and fibre intake with puberty timing: a cohort study among Chinese children.

ABSTRACT:

Background

Dietary phytoestrogens have been suggested to influence puberty timing, a critical stage for well-being in adulthood. We hypothesized that childhood soy intake might prospectively influence puberty timing and that dietary fibre and the key isoflavone metabolite equol might play roles.

Methods

Cox proportional hazard regression models were performed in 4781 children (2152 girls and 2629 boys) aged 6-8 years old from the Chinese Adolescent Cohort Study for whom a food frequency questionnaire at baseline and information about potential confounders were available. Anthropometry and pubertal status including age at Tanner stage 2 for breast development (B2) or age at the initiation of gonadal growth (G2), and age at menarche (M) or voice break (VB) were assessed annual

SUBMITTER: Xiong J 

PROVIDER: S-EPMC8978387 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature