Predictors of mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Better insight in patients' prognosis can help physicians to timely initiate advance care planning (ACP) discussions with patients with chronic obstructive pulmonary disease (COPD). We aimed to identify predictors of mortality.

Methods

We systematically searched databases Embase, PubMed, MEDLINE, Web of Science, and Cochrane Central in April 2020. Papers reporting on predictors or prognostic models for mortality at 3 months and up to 24 months were assessed on risk-of-bias. We performed a meta-analysis with a fixed or random-effects model, and evaluated the discriminative ability of multivariable prognostic models.

Results

We included 42 studies (49-418,251 patients); 18 studies were included in the meta-analysis. Significant predictors of mortality within

SUBMITTER: Owusuaa C 

PROVIDER: S-EPMC8978392 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature