Targeted specific inhibition of bacterial and Candida species by mesoporous Ag/Sn-SnO₂ composite nanoparticles: in silico and in vitro investigation.

ABSTRACT: Invasive bacterial and fungal infections have notably increased the burden on the health care system and especially in immune compromised patients. These invasive bacterial and fungal species mimic and interact with the host extracellular matrix and increase the adhesion and internalization into the host system. Further, increased resistance of traditional antibiotics/antifungal drugs led to the demand for other therapeutics and preventive measures. Presently, metallic nanoparticles have wide applications in health care sectors. The present study has been designed to evaluate the advantage of Ag/Sn-SnO₂ composite nanoparticles over the single oxide/metallic nanoparticles. By using in silico molecular docking approaches, herein we have evaluated the effects of Ag/Sn-SnO

SUBMITTER: Pandey M 

PROVIDER: S-EPMC8978812 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature