Association of Human Whole Blood NAD⁺ Contents With Aging.

ABSTRACT:

Background

NAD⁺, nicotinamide adenine dinucleotide, is mostly described to associate with the aging process. We aimed to investigate the association between human whole blood NAD⁺ contents and aging in a relative large-scale community-based population and further to address the gender impact on this association.

Methods

We recruited 1,518 participants aged over 18 years old and free of cardiovascular and any type of cancer from the Jidong community from 2019 to 2020. Whole blood NAD⁺ level was measured by cycling assay and LC-mass spectroscopy assay. The chronological age and clinical data were collected using standard questionnaires. The participants were divided into five groups according to their chronological age. General liner regression

SUBMITTER: Yang F 

PROVIDER: S-EPMC8979162 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature