Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols.

ABSTRACT: Signal amplification by reversible exchange (SABRE) hyperpolarisation is used to enhance the NMR signals of nicotine and acrolein in methanol-d₄ solutions of electronic cigarette aerosols. Consequently, detection of 74 μM nicotine is possible in just a single scan ¹H NMR spectrum. The first example of an aldehyde hyperpolarised using SABRE is demonstrated and we work towards novel real-world applications of SABRE-hyperpolarised NMR for chemical analysis.

SUBMITTER: Tickner BJ 

PROVIDER: S-EPMC8979170 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature