Immunostimulant Activity of Bacteria Isolated from Extreme Environments in Baja California Sur, Mexico: A Bioprospecting Approach.

ABSTRACT: Excessive use of antibiotics has led to an increase of pathogenic bacteria with multiple antibiotic resistance. Hypersaline and hyperthermal environments promote the development of several microorganisms that can potentially act as immunostimulants. Thus, the aim of this study was bioprospecting marine bacteria from these environments using mouse leukocytes as a cell model for assess immunostimulatory activity. Samples were taken from two evaporation ponds with 4 and 8% salinity (p/v) in a marine solar saltern (MSS) at Laguna Ojo de Liebre, Guerrero Negro and a shallow hydrothermal vent (SHV), Bahía Concepción under a mangrove forest both off Baja California Sur, México. From total number of isolates (N = 340), 267 were obtained from the MSS and 73 from the SHV. The 10 isolates that

SUBMITTER: Rodriguez-Valdez G 

PROVIDER: S-EPMC8980129 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature