Lymphocyte percentage as a valuable predictor of prognosis in lung cancer.

ABSTRACT: Lymphocytes and neutrophils are involved in the immune response against cancer. This study aimed to investigate the relationship between lymphocyte percentage/neutrophil percentage and the clinical characteristics of lung cancer patients, and to explore whether they could act as valuable predictors to ameliorate lung cancer prognosis. A total of 1312 patients were eligible to be recruited. Lymphocyte percentage and neutrophil percentage were classified based on their reference ranges. Survival curves were determined using Kaplan-Meier method, and univariate and multivariate cox regression analyses were performed to identify the significant predictors. Decision curve analysis was used to evaluate the clinical benefit. The results of both training and validation cohorts indicated that lympho

SUBMITTER: Huang H 

PROVIDER: S-EPMC8980931 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature