Efficacy of dezocine on preventing opioid-induced cough during general anaesthesia induction: a PRISMA-compliant systematic review and meta-analysis.

ABSTRACT:

Objectives

To systematically review the effects of dezocine (DZC) on the occurrence rate and severity of opioid-induced cough (OIC).

Design

Systematic review and meta-analysis DATA SOURCES: PubMed, Embase, Cochrane Library, Ovid, Web of Science as well as Chinese BioMedical Literature & Retrieval System, China National Knowledge Infrastructure, Wanfang and VIP Data were searched from 1978 to 31 December 2020.

Inclusion criteria

All randomised controlled trials (RCTs) comparing DZC with placebo on the occurrence rate and severity of OIC.

Data analysis

All data were analysed by using RevMan V.5.3. Each outcome was tested for heterogeneity, and randomised-effects or fixed-effects model was used in the presence or absence of significant heterogeneity.

Results

SUBMITTER: He LX 

PROVIDER: S-EPMC8981282 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature