How did the adoption of wP-pentavalent affect the global paediatric vaccine coverage rate? A multicountry panel data analysis.

ABSTRACT:

Objectives

Several studies have highlighted the effects of combination vaccines on immunisation coverage at the national or subnational level. This study examined the effects globally. Worldwide introduction of whole-cell pertussis pentavalent (wP-pentavalent) allowed estimation of incremental coverage effects of combination vaccines on the third doses of diphtheria, tetanus, pertussis (DTP3); hepatitis B (HepB3) and Haemophilus influenzae type B (Hib3).

Design

Multicountry panel data analysis.

Data sources

Country-level vaccine coverage data of WHO/UNICEF for the years 1980-2018.

Methods

Linear mixed models were used to estimate the effects of wP-pentavalent introduction by incorporating proxy variables to control for time trend and other time-dependent

SUBMITTER: Khan MM 

PROVIDER: S-EPMC8981334 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature