Replication of epidemiological associations of carpal tunnel syndrome in a UK population-based cohort of over 400,000 people.

ABSTRACT:

Introduction

Several phenotypic factors are associated in the literature with an increased risk of carpal tunnel syndrome (CTS). Along with female sex and older age, certain systemic diseases show an association with CTS, with varying degrees of evidence.

Methods

This study was performed using the UK Biobank resource - a cohort study of over 500,000 participants who have allowed linkage of phenotypic data with their medical records. We calculated the prevalence of CTS and a sex-specific prevalence ratio and compared the body mass index (BMI) between cases and controls. We performed a series of nested case-control studies to compute odds ratios for the association between CTS and three systemic diseases.

Results

There were 12,312 CTS cases within the curated UK Biobank

SUBMITTER: Wiberg A 

PROVIDER: S-EPMC8982328 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature