Naproxen release behaviour from graphene oxide/cellulose acetate composite nanofibers.

ABSTRACT: The present study investigated the effect of graphene oxide in cellulose acetate-based composite nanofibers on the transdermal delivery of naproxen. The composite nanofibers were successfully produced via the electrospinning process by directly mixing cellulose acetate, graphene oxide, and naproxen solution with varied compositions. The formation of the nanofibers was confirmed by electron microscopy and other characterization techniques to prove the existence of graphene oxide and naproxen itself. Surprisingly, graphene oxide encourages the production of nanofibers with smaller average diameter, higher conductivity, higher mechanical strength, and higher naproxen release from the cellulose acetate nanofibers. Once combined with naproxen, the composite nanofiber exhibited antibacter

SUBMITTER: Purnamasari W 

PROVIDER: S-EPMC8982341 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature