Assessing the cost-effectiveness of precision medicine: protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Precision medicine (PM) involves gene testing to identify disease risk, enable early diagnosis or guide therapeutic choice, and targeted gene therapy. We aim to perform a systematic review and meta-analysis to quantify the cost-effectiveness profile of PM stratified by intervention type, identify sources of heterogeneity in the value-for-money of PM.

Methods and analysis

We will perform a systematic search in Embase, MEDLINE, EconLit and CRD databases for studies published in English language or with translation in English between 1 January 2011 and 8 July 2021 on the topic of cost-effectiveness analysis of PM interventions. The focus will be on studies that reported health and economic outcomes. Study quality will be assessed using the Biases in Economic Studie

SUBMITTER: Chen W 

PROVIDER: S-EPMC8984003 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature