Impaired conditioned pain modulation was restored after a single exercise session in individuals with and without fibromyalgia.

ABSTRACT:

Introduction

Exercise is an effective nonpharmacological intervention for individuals with fibromyalgia syndrome (FMS); however, considerable variability is observed in their pain response after a single exercise session that could be due to differences in baseline central pain inhibition (ie, conditioned pain modulation [CPM]).

Objectives

This study examined the effect of isometric exercise on CPM in people with FMS and control participants. A subaim was to identify whether pain inhibition after exercise was due to differences in baseline CPM.

Methods

Twenty-one individuals with FMS (50.5 ± 14.9 years) and 22 age-matched and sex-matched controls (49.2 ± 13.3 years) participated in a familiarization session and 2 randomized experimental sessions: (1) low-intensity iso

SUBMITTER: Alsouhibani A 

PROVIDER: S-EPMC8984585 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature