Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome.

ABSTRACT: Acute stroke is associated with high morbidity and mortality. In the last decades, new therapies have been investigated with the aim of improving clinical outcomes in the acute phase post stroke onset. However, despite such advances, a large number of patients do not demonstrate improvement, furthermore, some unfortunately deteriorate. Thus, there is a need for additional treatments targeted to the individual patient. A potential therapeutic target is interventions to optimize cerebral perfusion guided by cerebral hemodynamic parameters such as dynamic cerebral autoregulation (dCA). This narrative led to the development of the INFOMATAS (Identifying New targets FOr Management And Therapy in Acute Stroke) project, designed to foster interventions directed towards understanding and improving

SUBMITTER: Nogueira RC 

PROVIDER: S-EPMC8985432 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature