Symptom burden and health-related quality of life in chronic kidney disease: A global systematic review and meta-analysis.

ABSTRACT:

Background

The importance of patient-reported outcome measurement in chronic kidney disease (CKD) populations has been established. However, there remains a lack of research that has synthesised data around CKD-specific symptom and health-related quality of life (HRQOL) burden globally, to inform focused measurement of the most relevant patient-important information in a way that minimises patient burden. The aim of this review was to synthesise symptom prevalence/severity and HRQOL data across the following CKD clinical groups globally: (1) stage 1-5 and not on renal replacement therapy (RRT), (2) receiving dialysis, or (3) in receipt of a kidney transplant.

Methods and findings

MEDLINE, PsycINFO, and CINAHL were searched for English-language cross-sectional/longitudinal st

SUBMITTER: Fletcher BR 

PROVIDER: S-EPMC8985967 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature