Measures of left atrial function predict incident heart failure in a low-risk general population: the Copenhagen City Heart Study.

ABSTRACT:

Aims

This study investigated left atrial (LA) parameters as measured on transthoracic echocardiography as predictors of incident heart failure (HF) in a community cohort.

Methods and results

In a large general population study (n = 2221), participants underwent a health examination with echocardiography. The maximum and minimum LA volumes indexed to body surface area (LAVImax and LAVImin) were measured and the LA emptying fraction (LAEF) and LA expansion index (LAEI) were calculated. Among 1951 participants without atrial fibrillation or significant valve disease, the mean age was 59 ± 16 years and 58% were women. At baseline, 1% (n = 16) had a left ventricular ejection fraction of <50%, 44% had hypertension, and 10% had diabetes. During follow-up (median 15.8 years, interqu

SUBMITTER: Andersen DM 

PROVIDER: S-EPMC8986599 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature