High-quality imaging of endolymphatic hydrops acquired in 7 minutes using sensitive hT₂W-3D-FLAIR reconstructed with magnitude and zero-filled interpolation.

ABSTRACT:

Background

It is still challenging to detect endolymphatic hydrops (EH) in patients with Meniere's disease (MD) using MRI. The aim of the present study was to optimize a sensitive technique generating strong contrast enhancement from minimum gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) while reliably detecting EH in the inner ear, including the apex.

Materials and methods

All imaging was performed using a 3.0 T MR system 24 h after intratympanic injection of low-dose Gd-DTPA. Heavily T2-weighted 3-dimensional fluid-attenuated inversion recovery reconstructed with magnitude and zero-filled interpolation (hT₂W-FLAIR-ZFI) was optimized and validated in phantom studies and compared with medium inversion time inversion recovery imaging with magnitude recons

SUBMITTER: Zou J 

PROVIDER: S-EPMC8986670 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature