SaliVISION: a rapid saliva-based COVID-19 screening and diagnostic test with high sensitivity and specificity.

ABSTRACT: The Coronavirus disease 2019 (COVID-19) pandemic-caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)- has posed a global threat and presented with it a multitude of economic and public-health challenges. Establishing a reliable means of readily available, rapid diagnostic testing is of paramount importance in halting the spread of COVID-19, as governments continue to ease lockdown restrictions. The current standard for laboratory testing utilizes reverse transcription quantitative polymerase chain reaction (RT-qPCR); however, this method presents clear limitations in requiring a longer run-time as well as reduced on-site testing capability. Therefore, we investigated the feasibility of a reverse transcription looped-mediated isothermal amplification (RT-LAMP)-based m

SUBMITTER: DeFina SM 

PROVIDER: S-EPMC8986854 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature