Ontology highlight
ABSTRACT:
SUBMITTER: Mastroianni A
PROVIDER: S-EPMC8987170 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Mastroianni Antonio A Greco Sonia S Urso Filippo F Mauro Maria Vittoria MV Vangeli Valeria V
Infection & chemotherapy 20220301 1
This brief report documents the safety and efficacy of high-dose tigecycline as a salvage-therapy in in a case series of five patients with serious central nervous system (CNS) rocky mountain spotted fever (RMSF). These severily ill patients were unable to take any oral drug therapy, parenteral doxycycline was unavailable and absorption of oral doxycycline was a concern in these critically ill patients. As far as we know, we report the successfull use of tigecycline for the treatment of ricketts ...[more]