Association of Obesity with Worse Operative and Oncologic Outcomes for Patients Undergoing Gastric Cancer Resection.

ABSTRACT:

Background

How obesity has an impact on operative and oncologic outcomes for gastric cancer patients is unclear, and the influence of obesity on response to neoadjuvant chemotherapy (NAC) has not been evaluated.

Methods

Patients who underwent curative gastrectomy for primary gastric cancer between 2000 and 2018 were retrospectively identified. After stratification for NAC, operative morbidity, mortality, overall survival (OS), and disease-specific survival (DSS) were compared among three body mass index (BMI) categories: normal BMI (< 25 kg/m²), mild obesity (25-35 kg/m²), and severe obesity (≥ 35 kg/m²).

Results

During the study period, 984 patients underwent upfront surgery, and 484 patients received NAC. Tumor stage did not differ a

SUBMITTER: Nakauchi M 

PROVIDER: S-EPMC8987625 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature