Ethiodized poppyseed oil-based contrast medium is superior to water-based contrast medium during hysterosalpingography regarding image quality improvement and fertility enhancement: A multicentric, randomized and controlled trial.

ABSTRACT:

Background

The efficacy of ethiodized poppyseed oil in hysterosalpingography (HSG) image quality and fertility enhancement has been revealed, but whether this HSG modality has similar effects in the Chinese population is still unclear.

Methods

Between July 18, 2017, and December 29, 2019, this multicentric, randomized, two-arm, clinical trial was performed involving 15 medical centers. Infertile women meeting HSG indications were randomly assigned to an oil group and a water group. The coprimary outcome included HSG image quality during HSG and fertility-enhancing effects of HSG. This study was registered on ClinicalTrials.gov (NCT03370575).

Findings

A total of 1026 subjects were randomly assigned to an oil group (N = 508) and a water group (N = 518). HS

SUBMITTER: Zhang J 

PROVIDER: S-EPMC8987810 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature