Systematic review and meta-analysis of the correlation between plasma homocysteine levels and coronary heart disease.

ABSTRACT:

Background

With the progresses in medical development in recent years, plasma homocysteine (Hcy) levels are considered to be an independent risk factor for the development of coronary heart disease (CHD). We hope to use the method of meta-analysis to systematically evaluate the relationship between plasma Hcy levels and CHD, for providing a basis for the prevention, diagnosis and treatment of CHD.

Methods

The PubMed, Cochrane and Embase databases were searched for case-control studies and cohort studies on the association between plasma Hcy levels and CHD from the database establishment to October 2021. Duplicate studies were re-excluded by Endnote X9 software. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) scale. All of the studies we included were stu

SUBMITTER: Wang B 

PROVIDER: S-EPMC8987819 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature