Association of Myocardial Fibrosis and Stroke Volume by Cardiovascular Magnetic Resonance in Patients With Severe Aortic Stenosis With Outcome After Valve Replacement: The British Society of Cardiovascular Magnetic Resonance AS700 Study.

ABSTRACT:

Importance

Low-flow severe aortic stenosis (AS) has higher mortality than severe AS with normal flow. The conventional definition of low-flow AS is an indexed stroke volume (SVi) by echocardiography less than 35 mL/m2. Cardiovascular magnetic resonance (CMR) is the reference standard for quantifying left ventricular volumes and function from which SVi by CMR can be derived.

Objective

To determine the association of left ventricular SVi by CMR with myocardial remodeling and survival among patients with severe AS after valve replacement.

Design, setting, and participants

This multicenter longitudinal cohort study was conducted between January 2003 and May 2015 across 6 UK cardiothoracic centers. Patients with severe AS listed for either surgical aortic valve replacement

SUBMITTER: Thornton GD 

PROVIDER: S-EPMC8988025 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature