Advances and Challenges in Intranasal Delivery of Antipsychotic Agents Targeting the Central Nervous System.

ABSTRACT: Treatment of central nervous system (CNS) disorders is challenging using conventional delivery strategies and routes of administration because of the presence of the blood-brain barrier (BBB). This BBB restricts the permeation of most of the therapeutics targeting the brain because of its impervious characteristics. Thus, the challenges of delivering the therapeutic agents across the BBB to the brain overcoming the issue of insufficient entry of neurotherapeutics require immediate attention for recovering from the issues by the use of modern platforms of drug delivery and novel routes of administration. Therefore, the advancement of drug delivery tools and delivering these tools using the intranasal route of drug administration have shown the potential of circumventing the BBB, thereby del

SUBMITTER: Pandey M 

PROVIDER: S-EPMC8988043 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature