Does a screening digital rectal exam provide actionable clinical utility in patients with an elevated PSA and positive MRI?

ABSTRACT:

Objective

To define the value of a digital rectal exam (DRE) in the prostate-magnetic resonance imaging (MRI) era. Prostate MRI is increasingly used in men with elevated prostate-specific antigen (PSA) prior to biopsy.

Methods

A retrospective study was performed in men with elevated PSA undergoing MRI followed by MRI fusion with systematic biopsy and men with elevated PSA/active surveillance with negative MRI followed by biopsy. Baseline clinicopathologic characteristics and DRE findings were collected. We examined performance of a positive DRE on sensitivity and specificity of diagnosing clinically significant prostate cancer (CSPC).

Results

A total of 339 patients had elevated PSA and positive MRI followed by MRI fusion guided with systematic biopsy. Pre-biopsy DRE

SUBMITTER: Chang CM 

PROVIDER: S-EPMC8988521 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature